More than 90 percent of UTIs are caused by E. coli, which is normally found in your intestinal tract. Problems only arise when this ordinary bacterium is present in high numbers in places where it shouldn’t be—like your urinary system. When normal E. coli gets into your urinary tract and multiplies, you experience the usual signs and symptoms of a UTI. The cell walls of each E. coli are covered with tiny fingerlike projections called fimbria allowing them to “stick” to the inner walls of your bladder and even work their way upward to your ureter and kidneys. Because they cling to your urinary organs, they can’t simply be washed out when you urinate. These little fingerlike projections are made of an amino acid-sugar complex called lectin, which makes them sticky. Lectin on the bacteria’s fimbria binds to mannose, which is produced by your cells and covers the internal lining of your urinary organs. This mannose allows the bacteria to adhere to you—like Velcro. But when you take D-mannose it sticks to the E. coli so it can be effectively “rinsed” out by your urination. Unfortunately for the E. coli, D-mannose ‘sticks’ to E. coli lectins even better than E. coli lectins ‘stick’ to human cells. When we take a large quantity of D-mannose, almost all of it spills into the urine through our kidneys, literally ‘coating’ any E.coli present so they can no longer ‘stick’ to the inside walls of the bladder and urinary tract. The E. coli are literally rinsed away with normal urination!

Research carried out on the positive effects of D-mannose found that D-mannose is an excellent alternative to antibiotics. Antibiotics often kill both the good and the bad cells in your body. However, D-mannose leaves the good cells alone while tackling only the bad. Further, as D-mannose is already found in your body as a natural substance, this form of medication does you no harm. It is absolutely natural and does not have any side effects.

More and more urologists are now recommending d-Mannose to prevent UTIs. A clinical trial with 300 women who struggled with recurrent UTIs showed d-Mannose as MORE efffective than prophlactic antibiotics and with less side effects:

“In a study of more than 300 women with a history of recurrent UTIs, researchers treated the women with either two grams of D-mannose, 50 milligrams of an antibiotic, or no treatment daily for six months. D-Mannose is a naturally occurring sugar that’s closely related to glucose.

Only 15 percent of those taking the D-mannose had a recurrent UTI compared to 20 percent for the antibiotic group (both of which were significantly lower than the no-treatment group). However, the incidence of side effects was significantly lower in the D-mannose group than the antibiotics group.”

http://www.ncbi.nlm.nih.gov/pubmed/24215164

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